Lyovapor™ L-300
First lab Freeze Dryer for continuous sublimation
With Infinite-Technology™, the Lyovapor™ L-300 is the first lab freeze dryer for continuous sublimation thanks to two alternately working condensers that are automatically cleaned. In addition, control the entire process remotely via mobile devices.
Features
Optimize your process by combining temperature difference with optional product temperature sensors for reliable endpoint determination.
An integrated steam generator melts the ice and cleans the condenser hygienically.
Easily read process parameters thanks to an adjustable display that can be placed at the front or on the side of the freeze dryer.
Adjust the shelf distance to suit your application needs. Link three manifold racks together for more versatility in your freeze-drying process.
The combination of interface, software and a user-friendly app enables you to continuously control and monitor your freeze-drying process from anywhere at any time.
Take advantage of the most advanced features of Lyovapor™ L-300 with the Lyovapor™ Software and a simple upgrade to Interface Pro.
Compare the Lyovapor™ L-300
Lyovapor™ L-300 Pro with 6 heating shelves
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Pro with 4 heating shelves
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Continuous with 24 manifold rack
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 4 non heating shelves, 12 manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Pro with 4 heating shelves, stoppering cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Continuous with 24 manifold rack
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 36 manifold rack
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 4 non heating shelves, 12 manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Pro with 6 heating shelves
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Pro with 4 heating shelves
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Pro with 4 heating shelves, stoppering cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Pro with 6 heating shelves, manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
Lyovapor™ L-300 Continuous with 36 manifold rack
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 6 non heating shelves, 12 manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Continuous with 6 non heating shelves, 12 manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature: -
- Drying shelf temperature tolerance: -
- User interphase:4.6 in
Lyovapor™ L-300 Pro with 6 heating shelves, manifold cover
- Condenser Capacity (L300):Unlimited (2 x ≤ 1 kg)
- Lowest condenser temperature:-105 °C
- Condensing capacity:≤ 12 kg/24h at 25°C ambient temperature
- Minimum system vacuum:≥ 0.04 mbar
- Drying shelf temperature:up to 60°C
- Drying shelf temperature tolerance:± 1.0 °C
- User interphase:7 in
"The Lyovapor™ L-300 is the highly automated freeze dryer with continuous defrosting and 36 manifold positions providing less instrument downtime. The usage in the laboratory with open access and in small molecule synthesis with high sample throughput are the key features for high productivity."David Wechsler - Medicinal Chemistry, Roche Pharma Research and Early Development, Basel
Related Parts & Accessories
Pirani / piezo pressure sensor, with cable for pressure regulation, Lyovapor
Pirani / piezo pressure sensor, with cable for pressure regulation with the BUCHI Lyovapors.
Manifold valve (EPDM, Silicone) with SJ 29/32 Fast and reliable connection of the sample to all BUCHI Lyovapors.
Manifold valve for fast sample connection to a Lyovapor L-200 or L-300. Made of EPDM/Silicone, with SJ 29/32 connection.
Set Distributor for ampules, Lyovapors Distributor for 19 ampules for direct connection to manifold valve
Adapter for 19 ampules for direct connection to manifold valve to one of the BUCHI Lyovapors.
Edwards scroll pump nXDS 10iC for Lyovapor L-300 10 qm/h No oil change and more resistance to organic solvents
Dry scroll vacuum pump (Edwards nXDS10iC) with high chemical stability and a pumping speed of 10 m3/h at 50 Hz and 60 Hz for the Lyovapor L-300.
Set Drying Bottle 800 mL, Lyovapor Wiede opening for easy access to the samples.
Beaker flask 800 mL with rubber cap for direct connection to manifold valves including filter paper 75 μm, 100 pcs. and O-ring, 2 pcs. Combine with the BUCHI Lyovapor™ instruments.
Drying Chamber 6 unheatable shelves Enrich the space in your BUCHI Lyovapor with the Drying chamber 6 shelves, including top cover and 6 shelves.
Acrylic glass Drying chamber with top cover and 6 non-heatable shelves for the BUCHI Lyovapors.
Manifold rack 24 positions, complete, Lyovapors Connect up to 24 sample to a Lyovapor with the Drying rack manifold 24, including 24 manifold valves and baseplate,
Connect up to 24 samples to a BUCHI Lyovapor with the Drying rack with 24 manifold valves and base plate.
Drying chamber 4 unheatable shelves including 4 unheatable shelves, chamber and top cover
The acrylic glass drying chamber with top cover and 4 non-heatable shelves is an accessory for the BUCHI Lyovapors.
Drying rack manifold 12, complete, Lyovapor includes. 12 manifold valves, rack and baseplate
Connect up to 12 samples to a BUCHI Lyovapor with the Drying rack with 12 manifold valves and base plate.
Drying Chamber 4 unheatable shelves & 12 manifolds Combine shelve and manifold freeze drying with the BUCHI Lyovapors with the Drying chamber manifold, 4 shelves (including top cover MF, 4 unheatbale shelves and 12 manifold valves)
Acrylic glass Drying chamber with top cover with 12 manifold valves and 4 non-heatable shelves for the BUCHI Lyovapors.
Drying Chamber with 4 heatable shelves, product temeprature sensors and top cover stoppering includes 4 heatable shelves, 4 product temperature sensors, top cover stoppering
The Drying Chamber With Stoppering is an accessory for the BUCHI Lyovapors Pro that has a stoppering cover, 4 heatable shelves and 4 sample temperature sensors. The accessory will help you ensure maximum control over the drying process.
Downloads
- Operation Manual Lyovapor L-300 en(pdf)
- Technical Data Sheet Lyovapor L-300(pdf)
- Solution Brochure Freeze Drying en(pdf)
- Product Brochure Pharma and Chemistry en(pdf)
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Related Courses & Trainings
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Applications
From standard application to unlimited ice capacity
Education
For a wide range of applications in academic education: Complete temperature sensitive drying.
Biotechnology
Used in biotechnology development for drying biologically active products: Drying and stabilization of small quantities in micro titer plates or small flasks.
Environmental Analysis
Required for sample preparation and stabilization to monitor environmental pollution: During storage of samples in order to destroy micro-organisms. Drying, e.g. for SpeedExtractor.
Chemical
For gentle and lossless drying in QC and R&D laboratories: Drying of most minute quantities in micro titer plates as well as small and large flasks or bulk drying is possible.
Food and Natural Extracts
Used for developing function-al food and analytics: Solvent is removed during, drying without destroying, the natural substances such as proteins, minerals or vitamins.
Pharmaceutical
For various applications in QC as well as laboratory scale synthesis and formulation in R&D departments: Drying of peptides and proteins of amorphous and crystalline solutions.
