Lyophilisation of mannitol and NaCl solutions in serum vials

In this Application Note sodium chloride (NaCl) and mannitol are used for freeze drying experiments. The unambiguous crystal structure of NaCl renders this salt a model compound. In contrast, mannitol is well known to crystallize in different polymorphs and it may form hydrates. Nevertheless, mannitol is the most used bulking agent for freeze dried pharmaceutical formulations. The benefits of using mannitol are that it crystallizes during freezing, creates a beautiful cake and permits drying processes at higher product temperatures, thus with higher sublimation rates compared to purely amorphous systems.

Lyophilisation of mannitol and NaCl solutions in serum vials

注册下载

国家
我们希望在将来向您发送您可能感兴趣的其他相关信息,例如应用文献、指南、网络会议和研讨会邀请。因此,我们希望和您保持联系。您可以在我们的隐私政策中了解您的权利以及我们如何使用和处理您的个人信息。

类似的应用