PLGA sub-micron particles by Nano Spray Drying

Aim of this Application Note is to give an application help in spray drying biodegradable polymers such as PLGA using the Nano Spray Dryer B-90 HP combined with the Inert Loop B-295. The use of the Inert Loop B-295 enables to dry solutions or suspensions of organic solvents in a fully closed system, maximizing user safety and minimizing solvent waste. Here, the polymer type and the influence of the concentration on the particles characteristics are studied.