Spray drying of paracetamol with the Nano Spray Dryer B-90
Spray drying is a scalable, rapid and drying is a scalable, rapid, and economic technique that allows that converting liquids into dry powders. Paracetamol (also known drug for fever reduction and pain relief with anti-inflammatory effects. In this study, the feasibility of the Nano Spray Dryer B-90 to spray dry paracetamol in combination with Kollidon® 30, a widely applied 30, a widely applied excipient in the excipient in the pharmaceutical and cosmetic industry, was tested. The investigations focused on the influence on particle size, residual solvent content, and morphology.
TKN determination in water and wastewater
SpeedDigester K-439, Kjel Line and MultiDist: Steam distillation and Potentiometric determination of Total Kjeldahl Nitrogen (TKN) according to the kjeldahl method in water and wastewater along with determination of Limit of Detection (LOD) and Limit of Quantification (LOQ).
L'utilisation de solvants organiques dans les lyophilisateurs de laboratoire
Freeze-dryers were initially intended to be used with water as a solvent. With new applications, freeze-drying is consequently being used more and more in combination with organic solvents instead of water. Organic solvents and inorganic acids and bases are often used in research and development prior to lyophilisation of the sample. The behavior of these new types of samples during freeze-drying must therefore be considered prior to the process.
Sulfated Ash Determination for Pharmaceutical Quality Control
The wet digestion is used to remove all carbonous material from the sample. The remaining inorganic content can be weighed out, resulting in the sulfated ash, or then be used for further elemental analysis. The digestion is performed using concentrated sulfuric acid while heating the mixture. The heat is ramped automatically using the BUCHI Wet Digester B-440. Once the sulfuric acid has digested the sample and is evaporated, the sample is eventually ashed in a muffle oven to remove any remaining organic material.