实验室冷冻干燥机中有机溶剂的使用
Freeze-dryers were initially intended to be used with water as a solvent. With new applications, freeze-drying is consequently being used more and more in combination with organic solvents instead of water. Organic solvents and inorganic acids and bases are often used in research and development prior to lyophilisation of the sample. The behavior of these new types of samples during freeze-drying must therefore be considered prior to the process.
冷冻干燥机最初预期是使用水作为溶剂的。随着应用范围不断扩大,化学应用领域出现越来越多不溶于水的产品。因此,冷冻干燥正越来越多结合有机溶剂使用,水逐渐被取代。
有机溶剂和无机酸和碱通常用于样品冷冻干燥之前的研究和开发。因此在流程开始之前必须考虑这些新的样品类型在冷冻干燥期间的行为。