Endpoint of freeze drying by pressure difference test
The pressure difference test on Lyovapor™ is used to determine the end of the primary drying phase. A range of water-solvent mixtures is analyzed to identify conditions enabling reliable implementation for this test.
As the pressure difference test employing two pressure gauges has proven to be effective for shelf applications, this study aims to evaluate this technique to determine the end of the primary drying phase in manifold application. It investigates the efficacy in determining drying endpoints and the advantages over traditional methods. A range of water-solvent mixtures is analyzed to identify conditions enabling reliable implementation. The precisely determined drying time can increase the reproducibility of drying result and ensure a dry product.
Register for download
Related Instruments
Lyovapor™ L-250
Introducing the Lyovapor™ L-250, featuring our groundbreaking EcoStream™ technology: the most eco-friendly freeze-drying solution for your laboratory. Our innovative cooling technology significantly lowers the environmental impact of the instrument without compromising our commitment to quality and reliability. BUCHI’s commitment to enhancing the sustainability of laboratory processes is certified with the ACT label for L-250 Basic and L-250 Pro configurations.
