Lyophilisation of mannitol and NaCl solutions in serum vials
In this Application Note sodium chloride (NaCl) and mannitol are used for freeze drying experiments. The unambiguous crystal structure of NaCl renders this salt a model compound. In contrast, mannitol is well known to crystallize in different polymorphs and it may form hydrates. Nevertheless, mannitol is the most used bulking agent for freeze dried pharmaceutical formulations. The benefits of using mannitol are that it crystallizes during freezing, creates a beautiful cake and permits drying processes at higher product temperatures, thus with higher sublimation rates compared to purely amorphous systems.
In this Application Note sodium chloride (NaCl) and mannitol are used for freeze drying experiments. The unambiguous crystal structure of NaCl renders this salt a model compound. In contrast, mannitol is well known to crystallize in different polymorphs and it may form hydrates. Nevertheless, mannitol is the most used bulking agent for freeze dried pharmaceutical formulations. The benefits of using mannitol are that it crystallizes during freezing, creates a beautiful cake and permits drying processes at higher product temperatures, thus with higher sublimation rates compared to purely amorphous systems.
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Lyovapor L-200
Sebagai pengering beku pertama dengan Infinite-Control™, Lyovapor L-200 yang ringkas ini menawarkan automasi yang tidak ada bandingannya dalam hal sublimasi. Buat dan jalankan dengan mudah berbagai metode, pencatatan data, perekaman data bagan dalam waktu nyata, dan berinteraksi dari mana saja dan kapan saja dengan perangkat seluler.
Lyovapor L-300
Dengan Infinite-Technology™, Lyovapor™ L-300 merupakan pengering beku skala laboratorium pertama untuk sublimasi berkelanjutan berkat adanya dua kondensor yang bekerja secara bergantian yang dibersihkan secara otomatis. Selain itu, kontrol keseluruhan proses dari jarak jauh melalui perangkat seluler.
