Separation of natural compounds by Flash chromatography
Separation of natural compounds.
Natural products play a significant role in the drug discovery and development process. They get modified to develop novel agents linking mother nature to combinatorial synthetic techniques. Scientists investigate all possible routes to these novel agents from terrestrial to marine environments. Natural product extracts have been shown to be complex for purification as they contain many different compounds with similar separation behaviours as well as critical components that are both chromophoric and non-chromophoric. The below example shows the isolation of eugenol and caryophyllene from a clove extract. Both compounds contain medicinal properties and are uused for treating various health disorders such as indigestion, cough, headaches, and stress.
