Spray Drying of Mannitol
Mannitol is a sugar alcohol that is widely used in the food, pharmaceutical, and medical industries. It is commonly produced by the hydrogenation of glucose and is used as a bulking agent, sweetener, and flavor enhancer. Spray drying is a commonly used technique for producing dry powders from liquids, and has been applied to mannitol to create a dry, free-flowing powder with improved handling and storage characteristics.
The process of spray drying involves atomizing a solution of mannitol into a stream of hot gas, which evaporates the solvent and leaves behind a fine powder. The resulting mannitol powder has a controlled particle size distribution, high purity, and improved solubility.
Spray drying of mannitol has been used in a variety of applications, including the production of inhalable drugs, chewable tablets, and sugar-free confectionery products. The process can be used to modify the properties of mannitol, such as controlling its particle size and surface area, and improving its flow and compressibility.
In summary, spray drying of mannitol is a promising technology that offers a way to produce a dry, free-flowing powder with improved handling and storage characteristics. Its applications extend to many different areas of the food, pharmaceutical, and medical industries, including the production of inhalable drugs, chewable tablets, and sugar-free confectionery products.
Please see the application note for starting paramters, formulations and some results.
