Spray Drying of PulmoSpheres
Spray drying is a commonly used technique for the production of powders from liquid solutions or suspensions. In pharmaceutical research and development, it is often used for the preparation of inhalable dry powders for respiratory drug delivery. PulmoSpheres are a type of inhalable powder that has been prepared using spray drying.
The process involves preparing a solution or suspension of drug particles and other excipients, such as carriers and stabilizers, and atomizing it into small droplets using a spray nozzle. The droplets are then passed through a drying chamber where they are exposed to a stream of hot air. As the droplets travel through the drying chamber, the solvent evaporates, leaving behind the dry powder.
The resulting PulmoSpheres powder is collected and characterized using various analytical techniques. PulmoSpheres are designed to have specific properties that allow for optimal deposition in the lungs, ensuring effective drug delivery.
Spray drying of PulmoSpheres is an efficient and effective method for the production of inhalable dry powders for respiratory drug delivery. It allows for the precise control of particle size, shape, and composition, resulting in a powder that is optimized for specific applications.
Please find starting paramters and some Results in this Application Note.
