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      FlashPure are prefilled cartridges offered in a wide range of sizes, covering different stationary phases, particle sizes and geometries. This enables the user to choose the flash cartridge which best suits his purification needs., html_buchi
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    • Separation of cannabinoids by Flash chromatography
      The compounds produced by the cannabis plant are famous for both recreational and medical purposes. The potency of the so-called cannabinoids in pharmaceutical applications, to ensure pain relief or to ease psychological burden, promoted the development of the cannabis industry. In many cases the challenge in this field is to purify the medically used substances from illegal psychoactive compounds. There are more than one hundred of cannabinoids identified, some of them having similar chemical structure. This feature complicates the separation of these compounds according to their chemical properties. Chromatography is the technique of choice for separation of multicomponents samples but when used at industrial scale, compromise has to be found between its separating power and the amount that can be purified. Larger capacity and loading are usually detrimental to the separation, i.e. they lower the resolution between the eluting substances. Flash-chromatography can be used to separate the most important components of cannabis extract despite its lower resolution. Depending on the criteria to isolate a given peak in the chromatogram, a high purity can be obtained without the need for baseline resolution. The material used for flash-chromatography also allows to increase the loading of sample to be purified, i.e. scale-up. Since scalling-up usually decreases the efficiency of separation, the process in chromatography is done by first optimizing the parameters for separation at a small-scale, before adaptation to the given size., html_buchi
      Separation of cannabinoids by Flash chromatography
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      Determination of trace metals by aqua regia digestion
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      <p>A simple and reliable procedure for fat determination of food and feed products according to Weibull-Stoldt is introduced. The sample is hydrolyzed with the HydrolEx H-506. The Soxhlet extraction is performed with the FatExtractor E-500. Calculation of total fat content follows gravimetrically after the extract has been dried to a constant weight.&nbsp;</p>, html_buchi
      Fat determination in dairy products by Soxhlet
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      BÜCHI Labortechnik AG expands its trusted Rotavapor® portfolio with the all-new Rotavapor® R-180—engineered for simplicity, reliability, and everyday performance. Accommodating flasks up to 3L, the cost-effective Rotavapor® R-180 is ideal for routine evaporation and fits neatly between the compact Rotavapor® R-80 (1L) and the fully automated Rotavapor® R-300 (5L).
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      2025 May. 8
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      ACT Ecolabel Certification attributed to the Lyovapor™ L-250 and the Rotavapor® R-80
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  1. Home
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Colorful researchers

Welcome to the "Colorful researchers" blog

This place helps chemists to discover the “Aha! Moment” of their research in a time-efficient and smart manner. Explore the shared resources, guidance and practical know-how to boost your inherent curiosity and pure love for science!

Colorful-researchers.jpg

Colorful researchers post overview

  • The Future is Supercritical: How SFC is Transforming Natural Product Analysis

    Padma explains how prep SFC can be utilized to effectively analyze and purify natural products by explaining each of the categories and how prep SFC benefits the process.

    009_The_Future_is_Supercritical_1200x1200.tiff
  • From Lab to Pharmacy: The Power of Spray Drying in Drug Development

    Bruno gives a brief overview of spray drying and explains how it can be used in drug development. Important equations and parameters are described, serving as the basis of the process optimization. 

    008_Drug_discovery_creation_1200x1200.tiff
  • Leveling Up: Embracing the Future of Evaporation

    Peter uses the level sensor as an example to explain how rotary evaporators combine physical, mechanical, and digital components in a symphony of science.

    007_Level_Sensor_1200x1200.tiff
  • Breaking the Bottleneck: Chromatography Columns and the Importance of Parallel Screening

    Padma explains how to speed up the chromatography process by using parallel column screening. The benefits of SFC over HPLC are also discussed.

    006_Speed_up_HPLC_and_SFC_Process_1200x1200.tiff
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