Spray Drying of Albumin
Spray Drying of Albumin with the Mini Spray Dryer B-290
Albumin is a protein found in animal blood plasma and is widely used in various medical, pharmaceutical, and research applications. Spray drying has been explored as a technique for the production of albumin powder, offering advantages such as improved stability, ease of handling, and enhanced preservation of its biological activity.
The areas of focus in spray drying of albumin include optimizing the process parameters, such as the inlet and outlet temperatures, atomizer type, and feed rate, to achieve the desired particle size, morphology, and preservation of functional proteins. Additionally, research has been conducted to evaluate the impact of different drying conditions and formulation additives on the physical and chemical properties of the powder, such as its solubility, reconstitution properties, and storage stability.
Furthermore, spray drying has been investigated as a method for producing albumin-based microparticles or nanoparticles, which can be used in various applications, such as drug delivery systems, tissue engineering, and vaccine formulations. These albumin-based particles offer versatility and controlled release properties, enabling targeted delivery and improved therapeutic efficacy.
Overall, Spray drying of albumin offers a promising approach for the production of stable and bioactive albumin powders, providing opportunities for their use in a wide range of medical, pharmaceutical, and biotechnological applications.
Please see the application note for starting parameters, formulations and some results.
