Spray Drying of Barium sulfate
Spray Drying of Barium sulfate with the Mini Spray Dryer B-290
Barium sulfate is a widely used contrast agent in medical imaging procedures, such as X-rays and CT scans. Spray drying has been explored as a technique for the production of barium sulfate powder, offering advantages such as improved dispersibility, particle size control, and ease of formulation.
The areas of focus in spray drying of barium sulfate include optimizing the process parameters, such as the inlet and outlet temperatures, atomizer type, and feed rate, to achieve the desired particle size distribution, morphology, and density of the powder. Additionally, research has been conducted to evaluate the impact of different drying conditions and formulation additives on the physical and chemical properties of the powder, such as its flowability, solubility, and radiopacity.
Furthermore, spray drying has been investigated as a method for producing barium sulfate-based formulations, such as suspensions or emulsions, for oral or intravenous administration. These formulations offer improved bioavailability, enhanced patient compliance, and precise imaging during diagnostic procedures.
Overall, spray drying of barium sulfate offers a promising approach for the production of high-quality powder and formulation development, providing improved properties and performance in medical imaging applications.
Please see the application note for starting paramters, formulations and some results.
