Spray Drying of Lonidamine
Application Note Mini Spray Dryer B-290 Lonidamine
Lonidamine is an anticancer drug that has poor solubility and bioavailability, limiting its effectiveness in cancer treatment. Spray drying has been investigated as a method for improving the solubility and bioavailability of lonidamine by producing a dry, fine powder formulation.
The main areas of spray drying of lonidamine include the pharmaceutical and biotechnology industries. In the pharmaceutical industry, spray-dried lonidamine powders are used as a therapeutic agent for the treatment of various cancers. In the biotechnology industry, spray-dried lonidamine powders are used as a research tool for the study of cancer biology and drug delivery.
Overall, spray drying of lonidamine has a specific application in the pharmaceutical and biotechnology industries. The use of spray drying can offer several advantages such as improved solubility, bioavailability, stability, and ease of handling, making it a preferred technique for the production of lonidamine powders in these industries. However, the optimization of the spray drying conditions and the characterization of the spray-dried powders are significant challenges that need to be addressed for the wider adoption of spray-dried lonidamine in industry.
Please see the application note for starting paramters, formulations and some results.
