Spray Drying of Cell suspension (anaerobe enterobacteria)
Spray Drying of Cell suspension (anaerobe enterobacteria) with the Mini Spray Dryer B-290
Anaerobic enterobacteria are a type of bacteria that can cause a range of infections in humans, such as gastrointestinal infections, urinary tract infections, and sepsis. Cell suspension is a method used to culture and maintain these bacteria in a liquid medium, which can then be used for various research or diagnostic purposes. Spray drying is a technique that can be used to convert the liquid cell suspension into a dry powder, which can have advantages for storage, transportation, and preparation of the bacterial sample.
The areas of focus in spray drying of anaerobic enterobacteria cell suspension include optimizing the process parameters, such as inlet temperature, outlet temperature, atomizer type, feed rate, and solvent composition, to achieve the desired particle size, morphology, and viability of the bacteria. Additionally, research has been conducted to evaluate the impact of different drying conditions on the survival rate and genetic stability of the bacterial sample, as well as its antigenicity and immunogenicity.
Other areas of interest include the development of novel formulations and delivery systems for the bacterial powder, such as vaccines or probiotics, which can improve their efficacy and safety. Spray drying has also been explored as a potential method for producing bacterial powders with tailored functional properties, such as improved adhesion or colonization ability. Overall, spray drying of anaerobic enterobacteria cell suspension offers a promising approach for improving the diagnosis and treatment of bacterial infections.
Please see the application note for starting paramters, formulations and some results.
