Spray Drying of Cromolyn sodium
Spray Drying of Cromolyn sodium with the Mini Spray Dryer B-290
Spray drying is a technique used to produce powders from liquids or solutions, which involves spraying the liquid into a hot gas stream to evaporate the solvent and produce fine particles. Cromolyn sodium is a medication used to prevent asthma attacks and allergic reactions by reducing inflammation in the airways.
Spray drying of cromolyn sodium has been extensively studied and applied in the pharmaceutical industry. Areas of focus in spray drying of cromolyn sodium include optimizing the process parameters such as inlet temperature, outlet temperature, atomizer type, feed rate, and solvent composition to achieve the desired particle size, morphology, and yield.
Other areas of research include the effect of excipients and processing aids on the physical and chemical stability of the cromolyn sodium powder, as well as the impact of the spray drying process on the drug's efficacy and bioavailability. Spray drying has also been explored as a potential method for pulmonary drug delivery of cromolyn sodium, as it can produce inhalable powders with controlled release properties.
Please see the application note for starting paramters, formulations and some results.
