Spray Drying of Human Growth Hormone
Human growth hormone (hGH) is a protein hormone secreted by the pituitary gland that plays a critical role in the growth and development of the human body. Spray drying is a promising technique used to produce dry powder formulations of hGH, which can improve the stability and shelf life of the hormone.
Spray drying of hGH requires careful optimization of several parameters, such as the type and concentration of the excipient, the drying temperature, and the feed rate. The final powder properties such as particle size, morphology, and hormone activity depend on these parameters.
The applications of spray-dried hGH powder are diverse and include the production of therapeutic drugs for the treatment of growth hormone deficiency, metabolic disorders, and other related conditions. The use of spray-dried hGH powder can improve the stability and shelf life of the hormone, reduce the dosage of the hormone needed, and provide a more convenient form of administration.
Overall, spray drying of hGH powder is an important process in the pharmaceutical industry, providing a stable and versatile powder form of the hormone with improved functional properties that can be applied in various therapeutic applications.
Please see the application note for starting paramters, formulations and some results.
