Nitrogen Determination in Pharmaceuticals

Nitrogen Determination in Pharmaceuticals according to the Kjeldahl Method (semi-micro)

Nitrogen determination is one of the key analyses performed in quality control. The samples require digestion with sulfuric acid to convert nitrogen into ammonium sulfate. After conversion to ammonia through the alkalinization with sodium hydroxide, the sample is distilled into a boric acid receiver by steam distillation, followed by a titration with hydrochloric acid solution.

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