Spray Drying of Insulin

Spray drying is a promising technology for the production of insulin powder formulations. This process involves the atomization of insulin solution into a spray of fine droplets, which are rapidly dried to form dry powder particles. The resulting powder is then filled into capsules or other dosage forms for oral administration.

Spray drying offers several advantages in the production of insulin formulations, including improved stability, bioavailability, and ease of administration. The dry powder form also eliminates the need for cold storage and transportation, making it more convenient for patients.

The use of spray drying in insulin production is particularly beneficial for developing new oral formulations of insulin, which can offer an alternative to injectable insulin. The technology also allows for the modification of the insulin particle size and surface properties, which can affect the absorption and bioavailability of the drug.

Overall, spray drying is a promising technology for the production of insulin powder formulations with improved stability, bioavailability, and ease of administration. It offers new opportunities for the development of oral formulations of insulin, which can improve patient compliance and quality of life.

Please see the application note for starting paramters, formulations and some results.

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