Spray Drying of Immunoglobulin
Immunoglobulin (Ig), also known as antibodies, are proteins produced by the immune system in response to foreign substances or pathogens. Spray drying is a promising technique for producing dry powders of immunoglobulin formulations that can improve the stability and handling of the material.
Spray drying of immunoglobulin powders requires careful optimization of several parameters, such as the type and concentration of the excipient, the drying temperature, and the feed rate. The final powder properties such as particle size, morphology, and purity depend on these parameters.
The applications of spray-dried immunoglobulin powder are diverse and include the production of therapeutics for autoimmune diseases, infectious diseases, and cancer. The use of spray-dried immunoglobulin powder can improve the bioactivity, stability, and solubility of the material, enhance its therapeutic efficacy, and provide a more convenient form of administration.
Overall, spray drying of immunoglobulin powder is an important process in the biopharmaceutical industry, providing a stable and versatile powder form of the material with improved functional properties that can be applied in various biologic drug delivery applications.
Please see the application note for starting paramters, formulations and some results.
