Spray drying has been used to prepare Oxyhemoglobin (OxyHb) nanoparticles, which are useful in drug delivery applications. The process involves the formation of OxyHb nanoparticles by spray drying a solution containing OxyHb and a biodegradable polymer such as poly(lactide-co-glycolide) (PLGA). Spray drying leads to the formation of a dry powder, which can be easily stored and transported.
OxyHb nanoparticles are being investigated for their use in targeted drug delivery systems, as they can be used to deliver drugs to specific tissues in the body. They can also be used to enhance the therapeutic efficacy of drugs, reduce their side effects and improve their bioavailability.
OxyHb nanoparticles have also been studied for their use in oxygen carriers for blood substitutes. Spray drying has been used to prepare OxyHb nanoparticles coated with a biocompatible polymer, which can be used as oxygen carriers in the treatment of anemia and other blood-related disorders.
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